منابع مشابه
Understanding niacin formulations.
Niacin is an important therapeutic option for the treatment of dyslipidemias and is the only agent currently available that favorably affects all components of the lipid profile to a significant degree. Niacin has consistently been shown to significantly reduce levels of total cholesterol, low-density lipoprotein (LDL) cholesterol, triglycerides, and lipoprotein (a), while having the greatest h...
متن کاملThe facts behind niacin.
Although low-density lipoprotein cholesterol (LDL-C) lowering represents the mainstay of current lipid treatment, high-density lipoprotein cholesterol (HDL-C) has generated increasing interest as a secondary therapeutic target because of strong evidence that serum HDL-C concentration is inversely associated with coronary heart disease risk. Niacin is a lipid-altering drug that has been used to ...
متن کاملExtended-release niacin/laropiprant: reducing niacin-induced flushing to better realize the benefit of niacin in improving cardiovascular risk factors.
Treatment with niacin effectively improves multiple lipid parameters and cardiovascular outcomes. Widespread use of niacin, however, is limited by flushing, which is mediated primarily by prostaglandin D2 (PGD2). Laropiprant is a selective PGD2 receptor 1 (DP1) antagonist that reduces objective measures of niacin-induced flushing symptoms upon initiation of therapy and with more chronic use. Re...
متن کاملNiacin and carcinogenesis.
The dietary status of niacin (vitamin B3) has the potential to influence DNA repair, genomic stability, and the immune system, eventually having an impact on cancer risk, as well as the side effects of chemotherapy in the cancer patient. In addition to its well-known redox functions in energy metabolism, niacin, in the form of NAD, participates in a wide variety of ADP-ribosylation reactions. P...
متن کاملNiacin in Maize *
Maize or Indian corn is, from the standpoint of total production, the second most important food plant in the world. No other crop is so widely distributed and only wheat occupies a larger acreage. Maize is noteworthy as a food because of its high content of carbohydrate, together with appreciable quantities of oil, protein, minerals, and other minor constituents. Food products made from field ...
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ژورنال
عنوان ژورنال: Advances in Nutrition
سال: 2016
ISSN: 2161-8313,2156-5376
DOI: 10.3945/an.115.011239